Howard Epps, a death row inmate, has less than two days left before his execution.When his attorney asks for Booth's help to prove his innocence, Booth agrees to look over the case and asks Brennan and her team to help him, even though he is convinced of Epps' guilt. After Brennan and her team help Booth identify a young woman found in a refrigerator, they proceed to find out who had killed the woman.
While Brennan is eager to examine the body, her colleagues want to go to the company's Christmas party.
When Zack cuts into the bones of the man, he accidentally releases a deadly fungus that causes the team, including Booth and Dr. Brennan and Booth investigate the body parts of a woman found in different locations by Los Angeles International Airport.
However, Brennan and her team have trouble identifying the victim when they discover that she had extensive cosmetic surgery done, which altered the core architecture of her skull.
An SUV explodes outside a cafe, killing several civilians. Brennan confirms the identity of the deceased driver to be the leader of the Arab-American Friendship League, the authorities suspect the man to be a terrorist.
Temperance Brennan is called in by FBI Special Agent Seeley Booth to aid an FBI investigation involving a set of bones found hidden in a lake.
Through examining the human remains of the driver, Brennan and her team are able to help Agent Booth to find the killer and stop a potential terrorist act involving the President. Brennan reluctantly joins Agent Booth to travel to Washington State, where a human arm was found inside the stomach of a bear.
As Brennan identifies the man, she discovers that he might have been a victim of a cannibal.
A six-year-boy's remains is found near a shopping mall and when he is confirmed by Dr.
Brennan to be the same boy who went missing from a local park, Booth and Brennan's team work together to find his murderer.
During a fight at a dance club, a wall breaks open to reveal a mummified corpse and a stash of methamphetamine.
When Brennan and her team identifies the deceased to be a former DJ of the dance club, Booth and Brennan investigate a rival DJ and the owner of the dance club.